Intestinal fatty acid‐binding protein and acute gastrointestinal injury grade in postoperative cardiac surgery patients

Background and Aim Gastrointestinal complications post cardiac surgery are infrequent but difficult to diagnose carry a high mortality. Plasma intestinal fatty acid-binding protein (I-FABP) concentrations the relationship between I-FABP, gastrointestinal dysfunction, postoperative outcomes were investigated in patients who developed dysfunction (acute injury [AGI] grade ≥2) those with normal function. Methods Patients (AGI 2 group, n = 11) without (matched controls, AGI 0 22) early extracted from larger single-center prospective observational study, including adults undergoing elective extracorporeal circulation, this nested case-control analysis. Results Both groups displayed variations I-FABP higher on Day 1 compared baseline Days 3 (p < .001 p .005, respectively). The group had .024). correlated positively over first days .036, .021 .018, High (defined as fourth quartile concentrations) was associated more prolonged surgical procedures .05). Furthermore, frequencies of organ .05) .05), 365-day Conclusion present study indicates an association intraoperative injury, complications. A high-powered is needed further explore interpretation individual patients.